Metformin Attenuates Experimental Autoimmune Arthritis through Reciprocal Regulation of Th17/Treg Balance and Osteoclastogenesis

Metformin is widely used to suppress certain functions of the cells found in diseases including diabetes and obesity. In this study, the effects of metformin on downregulating IL-17-producing T (Th17) cells, activating and upregulating regulatory T (Treg) cells, suppressing osteoclastogenesis, and c...

Descripción completa

Detalles Bibliográficos
Autores principales: Son, Hye-Jin, Lee, Jennifer, Lee, Seon-Yeong, Kim, Eun-Kyung, Park, Min-Jung, Kim, Kyoung-Woon, Park, Sung-Hwan, Cho, Mi-La
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158168/
https://www.ncbi.nlm.nih.gov/pubmed/25214721
http://dx.doi.org/10.1155/2014/973986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158168/
https://www.ncbi.nlm.nih.gov/pubmed/25214721
http://dx.doi.org/10.1155/2014/973986

Ejemplares similares