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A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements

Acute ethylene glycol ingestion classically presents with high anion gap acidosis, elevated osmolar gap, altered mental status, and acute renal failure. However, chronic ingestion of ethylene glycol is a challenging diagnosis that can present as acute kidney injury with subtle physical findings and...

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Autores principales: Toth-Manikowski, Stephanie M., Menn-Josephy, Hanni, Bhatia, Jasvinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158266/
https://www.ncbi.nlm.nih.gov/pubmed/25215251
http://dx.doi.org/10.1155/2014/128145
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author Toth-Manikowski, Stephanie M.
Menn-Josephy, Hanni
Bhatia, Jasvinder
author_facet Toth-Manikowski, Stephanie M.
Menn-Josephy, Hanni
Bhatia, Jasvinder
author_sort Toth-Manikowski, Stephanie M.
collection PubMed
description Acute ethylene glycol ingestion classically presents with high anion gap acidosis, elevated osmolar gap, altered mental status, and acute renal failure. However, chronic ingestion of ethylene glycol is a challenging diagnosis that can present as acute kidney injury with subtle physical findings and without the classic metabolic derangements. We present a case of chronic ethylene glycol ingestion in a patient who presented with acute kidney injury and repeated denials of an exposure history. Kidney biopsy was critical to the elucidation of the cause of his worsening renal function.
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spelling pubmed-41582662014-09-11 A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements Toth-Manikowski, Stephanie M. Menn-Josephy, Hanni Bhatia, Jasvinder Case Rep Nephrol Case Report Acute ethylene glycol ingestion classically presents with high anion gap acidosis, elevated osmolar gap, altered mental status, and acute renal failure. However, chronic ingestion of ethylene glycol is a challenging diagnosis that can present as acute kidney injury with subtle physical findings and without the classic metabolic derangements. We present a case of chronic ethylene glycol ingestion in a patient who presented with acute kidney injury and repeated denials of an exposure history. Kidney biopsy was critical to the elucidation of the cause of his worsening renal function. Hindawi Publishing Corporation 2014 2014-08-21 /pmc/articles/PMC4158266/ /pubmed/25215251 http://dx.doi.org/10.1155/2014/128145 Text en Copyright © 2014 Stephanie M. Toth-Manikowski et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Toth-Manikowski, Stephanie M.
Menn-Josephy, Hanni
Bhatia, Jasvinder
A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements
title A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements
title_full A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements
title_fullStr A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements
title_full_unstemmed A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements
title_short A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements
title_sort case of chronic ethylene glycol intoxication presenting without classic metabolic derangements
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158266/
https://www.ncbi.nlm.nih.gov/pubmed/25215251
http://dx.doi.org/10.1155/2014/128145
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