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NAMPT and NAPRT1: novel polymorphisms and distribution of variants between normal tissues and tumor samples

Nicotinamide phosphoribosyltransferase (NAMPT) and nicotinate phosphoribosyltransferase domain containing 1 (NAPRT1) are the main human NAD salvage enzymes. NAD regulates energy metabolism and cell signaling, and the enzymes that control NAD availability are linked to pathologies such as cancer and...

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Detalles Bibliográficos
Autores principales: Duarte-Pereira, Sara, Silva, Sarah S., Azevedo, Luísa, Castro, Luísa, Amorim, António, Silva, Raquel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158320/
https://www.ncbi.nlm.nih.gov/pubmed/25201160
http://dx.doi.org/10.1038/srep06311