Cargando…
Crucial involvement of xanthine oxidase in the intracellular signalling networks associated with human myeloid cell function
Xanthine oxidase (XOD) is an enzyme which plays a central role in purine catabolism by converting hypoxanthine into xanthine and then further into uric acid. Here we report that XOD is activated in THP-1 human myeloid cells in response to pro-inflammatory and growth factor stimulation. This effect o...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158321/ https://www.ncbi.nlm.nih.gov/pubmed/25200751 http://dx.doi.org/10.1038/srep06307 |