Crucial involvement of xanthine oxidase in the intracellular signalling networks associated with human myeloid cell function

Xanthine oxidase (XOD) is an enzyme which plays a central role in purine catabolism by converting hypoxanthine into xanthine and then further into uric acid. Here we report that XOD is activated in THP-1 human myeloid cells in response to pro-inflammatory and growth factor stimulation. This effect o...

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Detalles Bibliográficos
Autores principales: Abooali, Maryam, Lall, Gurprit S., Coughlan, Karen, Lall, Harjinder S., Gibbs, Bernhard F., Sumbayev, Vadim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158321/
https://www.ncbi.nlm.nih.gov/pubmed/25200751
http://dx.doi.org/10.1038/srep06307

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