Cargando…

Construction of human Fab library and screening of a single-domain antibody of amyloid-beta 42 oligomers

Screening humanized antibodies from a human Fab phage display library is an effective and quick method to obtain beta-amyloid oligomers. Thus, the present study prepared amyloid-beta 42 oli-gomers and constructed a naïve human Fab phage display library based on blood samples from six healthy people....

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Zuanning, Du, Minge, Chen, Yiwen, Dou, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158702/
https://www.ncbi.nlm.nih.gov/pubmed/25206631
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.33.004