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Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape

Microbiota regulate intestinal physiology by modifying host gene expression along the length of the intestine, but the underlying regulatory mechanisms remain unresolved. Transcriptional specificity occurs through interactions between transcription factors (TFs) and cis-regulatory regions (CRRs) cha...

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Detalles Bibliográficos
Autores principales: Camp, J. Gray, Frank, Christopher L., Lickwar, Colin R., Guturu, Harendra, Rube, Tomas, Wenger, Aaron M., Chen, Jenny, Bejerano, Gill, Crawford, Gregory E., Rawls, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158762/
https://www.ncbi.nlm.nih.gov/pubmed/24963153
http://dx.doi.org/10.1101/gr.165845.113