Blau syndrome polymorphisms in NOD2 identify nucleotide hydrolysis and helical domain 1 as signalling regulators

Understanding how single nucleotide polymorphisms (SNPs) lead to disease at a molecular level provides a starting point for improved therapeutic intervention. SNPs in the innate immune receptor nucleotide oligomerisation domain 2 (NOD2) can cause the inflammatory disorders Blau Syndrome (BS) and ear...

Descripción completa

Detalles Bibliográficos
Autores principales: Parkhouse, Rhiannon, Boyle, Joseph P., Monie, Tom P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158908/
https://www.ncbi.nlm.nih.gov/pubmed/25093298
http://dx.doi.org/10.1016/j.febslet.2014.07.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158908/
https://www.ncbi.nlm.nih.gov/pubmed/25093298
http://dx.doi.org/10.1016/j.febslet.2014.07.029

Ejemplares similares