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Oxidative stress activates AMPK in cultured cells primarily by increasing cellular AMP and/or ADP
AMPK is known to be activated by oxidative stress. Addition of glucose oxidase to cells generates H(2)O(2) at a constant rate that is opposed by enzymic degradation, providing a good model for physiological oxidative stress. AMPK activation by glucose oxidase correlated with increases in cellular AM...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons Ltd
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158911/ https://www.ncbi.nlm.nih.gov/pubmed/25084564 http://dx.doi.org/10.1016/j.febslet.2014.07.025 |