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Hydrogen sulphide suppresses human atrial fibroblast proliferation and transformation to myofibroblasts

Cardiac fibroblasts are crucial in pathophysiology of the myocardium whereby their aberrant proliferation has significant impact on cardiac function. Hydrogen sulphide (H(2)S) is a gaseous modulator of potassium channels on cardiomyocytes and has been reported to attenuate cardiac fibrosis. Yet, the...

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Detalles Bibliográficos
Autores principales: Sheng, Jingwei, Shim, Winston, Wei, Heming, Lim, Sze Yun, Liew, Reginald, Lim, Tien Siang, Ong, Boon Hean, Chua, Yeow Leng, Wong, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159014/
https://www.ncbi.nlm.nih.gov/pubmed/23945069
http://dx.doi.org/10.1111/jcmm.12114