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Brucine suppresses colon cancer cells growth via mediating KDR signalling pathway

Angiogenesis plays an important role in colon cancer development. This study aimed to demonstrate the effect of brucine on tumour angiogenesis and its mechanism of action. The anti-angiogenic effect was evaluated on the chicken chorioallantoic membrane (CAM) model and tube formation. The mechanism w...

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Detalles Bibliográficos
Autores principales: Luo, Wenjuan, Wang, Xiaoli, Zheng, Lei, Zhan, Yingzhuan, Zhang, Dongdong, Zhang, Jie, Zhang, Yanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159018/
https://www.ncbi.nlm.nih.gov/pubmed/23905676
http://dx.doi.org/10.1111/jcmm.12108