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A novel human anti-VCAM-1 monoclonal antibody ameliorates airway inflammation and remodelling

Asthma is a chronic inflammatory disease induced by Type 2 helper T cells and eosinophils. Vascular cell adhesion molecule-1 (VCAM-1) has been implicated in recruiting eosinophils and lymphocytes to pathological sites in asthma as a regulatory receptor. Accordingly, monoclonal antibody (mAb) against...

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Detalles Bibliográficos
Autores principales: Lee, Jae-Hyun, Sohn, Jung-Ho, Ryu, Su Yeon, Hong, Chein-Soo, Moon, Kyung D, Park, Jung-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159019/
https://www.ncbi.nlm.nih.gov/pubmed/23855490
http://dx.doi.org/10.1111/jcmm.12102