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Fission Yeast Pxd1 Promotes Proper DNA Repair by Activating Rad16(XPF) and Inhibiting Dna2

Structure-specific nucleases play crucial roles in many DNA repair pathways. They must be precisely controlled to ensure optimal repair outcomes; however, mechanisms of their regulation are not fully understood. Here, we report a fission yeast protein, Pxd1, that binds to and regulates two structure...

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Detalles Bibliográficos
Autores principales: Zhang, Jia-Min, Liu, Xiao-Man, Ding, Yue-He, Xiong, Liang-Yao, Ren, Jing-Yi, Zhou, Zhi-Xiong, Wang, Hai-Tao, Zhang, Mei-Jun, Yu, Yang, Dong, Meng-Qiu, Du, Li-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159138/
https://www.ncbi.nlm.nih.gov/pubmed/25203555
http://dx.doi.org/10.1371/journal.pbio.1001946