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Infection with Host-Range Mutant Adenovirus 5 Suppresses Innate Immunity and Induces Systemic CD4+ T Cell Activation in Rhesus Macaques

Ad5 is a common cause of respiratory disease and an occasional cause of gastroenteritis and conjunctivitis, and seroconversion before adolescence is common in humans. To gain some insight into how Ad5 infection affects the immune system of rhesus macaques (RM) 18 RM were infected with a host-range m...

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Detalles Bibliográficos
Autores principales: Qureshi, Huma, Genescà, Meritxell, Fritts, Linda, McChesney, Michael B., Robert-Guroff, Marjorie, Miller, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159191/
https://www.ncbi.nlm.nih.gov/pubmed/25203111
http://dx.doi.org/10.1371/journal.pone.0106004