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Effect of rosuvastatin on diabetic polyneuropathy: a randomized, double-blind, placebo-controlled Phase IIa study

BACKGROUND: Diabetic neuropathy affects 50%–66% of patients with diabetes mellitus. Oxidative stress generates nerve dysfunction by causing segmental demyelinization and axonal degeneration. Antioxidants are considered to be the only etiologic management for diabetic polyneuropathy, and statins such...

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Detalles Bibliográficos
Autores principales: Hernández-Ojeda, Jaime, Román-Pintos, Luis Miguel, Rodríguez-Carrízalez, Adolfo Daniel, Troyo-Sanromán, Rogelio, Cardona-Muñoz, Ernesto Germán, Alatorre-Carranza, María del Pilar, Miranda-Díaz, Alejandra Guillermina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159311/
https://www.ncbi.nlm.nih.gov/pubmed/25214797
http://dx.doi.org/10.2147/DMSO.S65500