Cargando…

Effect of rosuvastatin on diabetic polyneuropathy: a randomized, double-blind, placebo-controlled Phase IIa study

BACKGROUND: Diabetic neuropathy affects 50%–66% of patients with diabetes mellitus. Oxidative stress generates nerve dysfunction by causing segmental demyelinization and axonal degeneration. Antioxidants are considered to be the only etiologic management for diabetic polyneuropathy, and statins such...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hernández-Ojeda, Jaime, Román-Pintos, Luis Miguel, Rodríguez-Carrízalez, Adolfo Daniel, Troyo-Sanromán, Rogelio, Cardona-Muñoz, Ernesto Germán, Alatorre-Carranza, María del Pilar, Miranda-Díaz, Alejandra Guillermina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159311/ https://www.ncbi.nlm.nih.gov/pubmed/25214797 http://dx.doi.org/10.2147/DMSO.S65500

Ejemplares similares

Effects of Ezetimibe/Simvastatin and Rosuvastatin on Oxidative Stress in Diabetic Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
por: Villegas-Rivera, Geannyne, et al.
Publicado: (2015)

Diabetic Polyneuropathy in Type 2 Diabetes Mellitus: Inflammation, Oxidative Stress, and Mitochondrial Function
por: Román-Pintos, Luis Miguel, et al.
Publicado: (2016)

Effect of statins on oxidative DNA damage in diabetic polyneuropathy
por: Carrillo-Ibarra, Sandra, et al.
Publicado: (2018)

The Role of Oxidative Stress, Mitochondrial Function, and Autophagy in Diabetic Polyneuropathy
por: Sifuentes-Franco, Sonia, et al.
Publicado: (2017)

The effect of ubiquinone and combined antioxidant therapy on oxidative stress markers in non-proliferative diabetic retinopathy: A phase IIa, randomized, double-blind, and placebo-controlled study
por: Rodríguez-Carrizalez, Adolfo Daniel, et al.
Publicado: (2015)

The antioxidant effect of ubiquinone and combined therapy on mitochondrial function in blood cells in non-proliferative diabetic retinopathy: A randomized, double-blind, phase IIa, placebo-controlled study
por: Rodríguez-Carrizalez, Adolfo Daniel, et al.
Publicado: (2016)

Toll-Like Receptor-1 and Receptor-2 and Beta-Defensin in Postcholecystectomy Bile Duct Injury
por: Miranda-Díaz, Alejandra Guillermina, et al.
Publicado: (2015)

The Role of Oxidative Stress in Physiopathology and Pharmacological Treatment with Pro- and Antioxidant Properties in Chronic Diseases
por: García-Sánchez, Andrés, et al.
Publicado: (2020)

Foods with Potential Prooxidant and Antioxidant Effects Involved in Parkinson's Disease
por: Miranda-Díaz, Alejandra Guillermina, et al.
Publicado: (2020)

The Role of Cardiolipin and Mitochondrial Damage in Kidney Transplant
por: Miranda-Díaz, Alejandra Guillermina, et al.
Publicado: (2019)

Oxidants, antioxidants and mitochondrial function in non-proliferative diabetic retinopathy
por: Rodríguez-Carrizalez, Adolfo Daniel, et al.
Publicado: (2014)

Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology
por: Cecilia, Olvera-Montaño, et al.
Publicado: (2019)

Toll-Like Receptors in Secondary Obstructive Cholangiopathy
por: Miranda-Díaz, A. G., et al.
Publicado: (2011)

Prevalence of Toxoplasma Infection in Mexican Newborns and Children: A Systematic Review from 1954 to 2009
por: Galvan-Ramírez, Ma. de la Luz, et al.
Publicado: (2012)

Adjuvant Therapies in Diabetic Retinopathy as an Early Approach to Delay Its Progression: The Importance of Oxidative Stress and Inflammation
por: Robles-Rivera, Ricardo Raúl, et al.
Publicado: (2020)

Markers of Oxidative Stress and Inflammation in Ascites and Plasma in Patients with Platinum-Sensitive, Platinum-Resistant, and Platinum-Refractory Epithelial Ovarian Cancer
por: Cantón-Romero, Juan Carlos, et al.
Publicado: (2017)

Current Perspectives on rosuvastatin
por: Hu, Miao, et al.
Publicado: (2013)

Seroepidemiology of Toxoplasma gondii infection in drivers involved in road traffic accidents in the metropolitan area of Guadalajara, Jalisco, Mexico
por: Galván-Ramírez, Ma de la Luz, et al.
Publicado: (2013)

Genetic biomarkers related to hemarthrosis, inflammation, and cartilage structure in pediatric patients with hemophilic arthropathy
por: López‐Jiménez, José de Jesús, et al.
Publicado: (2019)

Rosuvastatin and chronic hepatitis C
por: Yoshida, Eric M.
Publicado: (2011)

Rosuvastatin induced photolocalized purpura
por: Thabouti, Marwa, et al.
Publicado: (2022)

Placebo effect in chronic inflammatory demyelinating polyneuropathy: The PATH study and a systematic review
por: Lewis, Richard A., et al.
Publicado: (2020)

Effects of perioperative rosuvastatin on postoperative delirium in elderly patients: A randomized, double-blind, and placebo-controlled trial
por: Xu, Xiao-Qin, et al.
Publicado: (2021)

Comparison of the effect of rosuvastatin versus rosuvastatin/ezetimibe on markers of inflammation in patients with acute myocardial infarction
por: Ren, Yizhi, et al.
Publicado: (2017)

Efficacy of Locally Administered 1.2% Rosuvastatin Gel in Patients with Periodontitis: A Randomized Placebo Controlled Clinical Trial
por: Chatterjee, Debopriya, et al.
Publicado: (2019)

Efficacy and safety of rosuvastatin in the management of dyslipidemia
por: Rubba, Paolo, et al.
Publicado: (2009)

Preparation and optimization of microemulsion of rosuvastatin calcium
por: Patel, Zalak B., et al.
Publicado: (2012)

Rosuvastatin-Induced Acute Interstitial Nephritis
por: Londrino, Francesco, et al.
Publicado: (2013)

The influence of the intestinal microflora to the efficacy of Rosuvastatin
por: Wang, Lijun, et al.
Publicado: (2018)

Diphtheritic Polyneuropathy
por: Joob, Beuy, et al.
Publicado: (2019)

Effects of high rosuvastatin doses on hepatocyte mitochondria of hypercholesterolemic mice
por: Díaz-Zagoya, Juan C., et al.
Publicado: (2021)

Lipid lowering efficacy and safety of Ezetimibe combined with rosuvastatin compared with titrating rosuvastatin monotherapy in HIV-positive patients
por: Saeedi, Ramesh, et al.
Publicado: (2015)

The Oxidative and Inflammatory State in Patients with Acute Renal Graft Dysfunction Treated with Tacrolimus
por: Carrillo-Ibarra, Sandra, et al.
Publicado: (2016)

Generation of polyclonal antibody with high avidity to rosuvastatin and its use in development of highly sensitive ELISA for determination of rosuvastatin in plasma
por: Darwish, Ibrahim A, et al.
Publicado: (2011)

Relationship between the Diabetic Polyneuropathy Index and the Neurological Findings of Diabetic Polyneuropathy
por: Hemmi, Shoji, et al.
Publicado: (2020)

Hepatotoxicity Associated with a Short Course of Rosuvastatin
por: Hwang, Na Kyoung, et al.
Publicado: (2015)

Effect and Safety of Rosuvastatin in Acute Ischemic Stroke
por: Heo, Ji Hoe, et al.
Publicado: (2016)

Examination of Physiologically‐Based Pharmacokinetic Models of Rosuvastatin
por: Bowman, Christine M., et al.
Publicado: (2020)

Exploring the molecular reorientations in amorphous rosuvastatin calcium
por: Belozerova, N. M., et al.
Publicado: (2020)

Rosuvastatin-Induced Rhabdomyolysis: A Case Report
por: Nikalji, Ravindra, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2aekkkgu4eu3oqbrklsscrig3a