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Characterization and evaluation of amine-modified graphene amphotericin B for the treatment of visceral leishmaniasis: in vivo and in vitro studies

Amphotericin B (AmB) has been the first-line treatment for visceral leishmaniasis (VL), a neglected protozoan disease, especially in regions like Bihar, India, where resistance to antimonials is widespread. However, adverse drug reactions are a major limiting factor. We evaluated a novel formulation...

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Detalles Bibliográficos
Autores principales: Mudavath, Shyam Lal, Talat, Mahe, Rai, Madhukar, Srivastava, Onkar Nath, Sundar, Shyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159315/
https://www.ncbi.nlm.nih.gov/pubmed/25214767
http://dx.doi.org/10.2147/DDDT.S63994