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Regulation of the Tumor Suppressor FOXO3 by the Thromboxane-A(2) Receptors in Urothelial Cancer
The transcription factor FOXO3 is a well-established tumor suppressor whose activity, stability, and localization are regulated by phosphorylation and acetylation. Previous data by our laboratory demonstrated amplified thromboxane-A(2) signaling was associated with poor prognoses in bladder cancer p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159332/ https://www.ncbi.nlm.nih.gov/pubmed/25202904 http://dx.doi.org/10.1371/journal.pone.0107530 |