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Regulation of the Tumor Suppressor FOXO3 by the Thromboxane-A(2) Receptors in Urothelial Cancer

The transcription factor FOXO3 is a well-established tumor suppressor whose activity, stability, and localization are regulated by phosphorylation and acetylation. Previous data by our laboratory demonstrated amplified thromboxane-A(2) signaling was associated with poor prognoses in bladder cancer p...

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Detalles Bibliográficos
Autores principales: Sobolesky, Philip M., Halushka, Perry V., Garrett-Mayer, Elizabeth, Smith, Michael T., Moussa, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159332/
https://www.ncbi.nlm.nih.gov/pubmed/25202904
http://dx.doi.org/10.1371/journal.pone.0107530