Non-canonical Wnt4 prevents skeletal aging and inflammation by inhibiting NF-κB

Aging-related bone loss and osteoporosis affect millions of patients worldwide. Chronic inflammation associated with aging and arthritis promotes bone resorption and impairs bone formation. Here we show that Wnt4 attenuated bone loss in osteoporosis and skeletal aging by inhibiting nuclear factor-ka...

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Detalles Bibliográficos
Autores principales: Yu, Bo, Chang, Jia, Liu, Yunsong, Li, Jiong, Kevork, Kareena, Al-Hezaimi, Khalid, Graves, Dana T, Park, No-Hee, Wang, Cun-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159424/
https://www.ncbi.nlm.nih.gov/pubmed/25108526
http://dx.doi.org/10.1038/nm.3586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159424/
https://www.ncbi.nlm.nih.gov/pubmed/25108526
http://dx.doi.org/10.1038/nm.3586

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