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Non-canonical Wnt4 prevents skeletal aging and inflammation by inhibiting NF-κB
Aging-related bone loss and osteoporosis affect millions of patients worldwide. Chronic inflammation associated with aging and arthritis promotes bone resorption and impairs bone formation. Here we show that Wnt4 attenuated bone loss in osteoporosis and skeletal aging by inhibiting nuclear factor-ka...
Autores principales: | Yu, Bo, Chang, Jia, Liu, Yunsong, Li, Jiong, Kevork, Kareena, Al-Hezaimi, Khalid, Graves, Dana T, Park, No-Hee, Wang, Cun-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159424/ https://www.ncbi.nlm.nih.gov/pubmed/25108526 http://dx.doi.org/10.1038/nm.3586 |
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