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A mammalian acetate switch regulates stress erythropoiesis

Endocrine erythropoietin (Epo), which is synthesized in the kidney or liver of adult mammals, controls erythrocyte production and is regulated by the stress-responsive transcription factor Hypoxia Inducible Factor 2 (HIF-2). We previously reported that the lysine acetyltransferase Cbp is required fo...

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Detalles Bibliográficos
Autores principales: Xu, Min, Nagati, Jason S., Xie, Jian, Li, Jiwen, Walters, Holly, Moon, Young-Ah, Gerard, Robert D., Huang, Chou-Long, Comerford, Sarah A., Hammer, Robert E., Horton, Jay D., Chen, Rui, Garcia, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159437/
https://www.ncbi.nlm.nih.gov/pubmed/25108527
http://dx.doi.org/10.1038/nm.3587