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Is there a risk of prion-like disease transmission by Alzheimer- or Parkinson-associated protein particles?

The misfolding and aggregation of endogenous proteins in the central nervous system is a neuropathological hallmark of Alzheimer’s disease (AD), Parkinson’s disease (PD), as well as prion diseases. A molecular mechanism referred to as “nucleation-dependent aggregation” is thought to underlie this ne...

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Detalles Bibliográficos
Autores principales: Beekes, Michael, Thomzig, Achim, Schulz-Schaeffer, Walter J., Burger, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159603/
https://www.ncbi.nlm.nih.gov/pubmed/25073522
http://dx.doi.org/10.1007/s00401-014-1324-9