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Is there a risk of prion-like disease transmission by Alzheimer- or Parkinson-associated protein particles?
The misfolding and aggregation of endogenous proteins in the central nervous system is a neuropathological hallmark of Alzheimer’s disease (AD), Parkinson’s disease (PD), as well as prion diseases. A molecular mechanism referred to as “nucleation-dependent aggregation” is thought to underlie this ne...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159603/ https://www.ncbi.nlm.nih.gov/pubmed/25073522 http://dx.doi.org/10.1007/s00401-014-1324-9 |