Cargando…

Stage of Breast Cancer Progression Influences Cellular Response to Activation of the WNT/Planar Cell Polarity Pathway

Planar cell polarity (PCP) signaling has been shown in different studies to either promote or inhibit the malignancy of breast cancer. Using the 21T cell lines, which were derived from an individual patient and represent distinct stages of progression, we show that the prototypical PCP ligand, WNT5A...

Descripción completa

Detalles Bibliográficos
Autores principales: MacMillan, Connor D., Leong, Hon S., Dales, David W., Robertson, Amy E., Lewis, John D., Chambers, Ann F., Tuck, Alan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159636/
https://www.ncbi.nlm.nih.gov/pubmed/25204426
http://dx.doi.org/10.1038/srep06315