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Stage of Breast Cancer Progression Influences Cellular Response to Activation of the WNT/Planar Cell Polarity Pathway
Planar cell polarity (PCP) signaling has been shown in different studies to either promote or inhibit the malignancy of breast cancer. Using the 21T cell lines, which were derived from an individual patient and represent distinct stages of progression, we show that the prototypical PCP ligand, WNT5A...
Autores principales: | MacMillan, Connor D., Leong, Hon S., Dales, David W., Robertson, Amy E., Lewis, John D., Chambers, Ann F., Tuck, Alan B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159636/ https://www.ncbi.nlm.nih.gov/pubmed/25204426 http://dx.doi.org/10.1038/srep06315 |
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