Reprogramming Human Endothelial to Hematopoietic Cells Requires Vascular Induction

Generating engraftable human hematopoietic cells from autologous tissues promises new therapies for blood diseases. Directed differentiation of pluripotent stem cells yields hematopoietic cells that poorly engraft. Here, we devised a method to phenocopy the vascular-niche microenvironment of hemogen...

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Detalles Bibliográficos
Autores principales: Sandler, Vladislav M., Lis, Raphael, Liu, Ying, Kedem, Alon, James, Daylon, Elemento, Olivier, Butler, Jason M., Scandura, Joseph M., Rafii, Shahin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159670/
https://www.ncbi.nlm.nih.gov/pubmed/25030167
http://dx.doi.org/10.1038/nature13547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159670/
https://www.ncbi.nlm.nih.gov/pubmed/25030167
http://dx.doi.org/10.1038/nature13547

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