Bioinformatics Study of Cancer-Related Mutations within p53 Phosphorylation Site Motifs

p53 protein has about thirty phosphorylation sites located at the N- and C-termini and in the core domain. The phosphorylation sites are relatively less mutated than other residues in p53. To understand why and how p53 phosphorylation sites are rarely mutated in human cancer, using a bioinformatics...

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Detalles Bibliográficos
Autores principales: Ji, Xiaona, Huang, Qiang, Yu, Long, Nussinov, Ruth, Ma, Buyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159794/
https://www.ncbi.nlm.nih.gov/pubmed/25075982
http://dx.doi.org/10.3390/ijms150813275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159794/
https://www.ncbi.nlm.nih.gov/pubmed/25075982
http://dx.doi.org/10.3390/ijms150813275

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