Dose-Dependent Protective Effect of Lithium Chloride on Retinal Ganglion Cells Is Interrelated with an Upregulated Intraretinal BDNF after Optic Nerve Transection in Adult Rats

Neuroprotection of lithium for axotomized retinal ganglion cells (RGCs) is attributed to upregulated intraretinal Bcl-2. As lithium also upregulates brain-derived neurotrophic factor (BDNF) which can rescue axotomized RGCs, it is hypothesized that lithium could protect RGCs through BDNF. This study...

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Detalles Bibliográficos
Autores principales: Wu, Ming-Mei, Zhu, Ting-Ting, Wang, Peng, Kuang, Fang, Hao, Ding-Jun, You, Si-Wei, Li, Yao-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159810/
https://www.ncbi.nlm.nih.gov/pubmed/25100168
http://dx.doi.org/10.3390/ijms150813550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159810/
https://www.ncbi.nlm.nih.gov/pubmed/25100168
http://dx.doi.org/10.3390/ijms150813550

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