Epigenetic Determinants of CYP1A1 Induction by the Aryl Hydrocarbon Receptor Agonist 3,3',4,4',5-Pentachlorobiphenyl (PCB 126)

Many enzymes involved in xenobiotic metabolism, including cytochrome P450 (CYP) 1A1, are regulated by the aryl hydrocarbon receptor (AhR). 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) is a potent ligand for AhR and can thus induce the expression of CYP1A1. Interestingly, we observed that huma...

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Detalles Bibliográficos
Autores principales: Vorrink, Sabine U., Hudachek, Danielle R., Domann, Frederick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159831/
https://www.ncbi.nlm.nih.gov/pubmed/25116688
http://dx.doi.org/10.3390/ijms150813916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159831/
https://www.ncbi.nlm.nih.gov/pubmed/25116688
http://dx.doi.org/10.3390/ijms150813916

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