Cargando…

Epigenetic Determinants of CYP1A1 Induction by the Aryl Hydrocarbon Receptor Agonist 3,3',4,4',5-Pentachlorobiphenyl (PCB 126)

Many enzymes involved in xenobiotic metabolism, including cytochrome P450 (CYP) 1A1, are regulated by the aryl hydrocarbon receptor (AhR). 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) is a potent ligand for AhR and can thus induce the expression of CYP1A1. Interestingly, we observed that huma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vorrink, Sabine U., Hudachek, Danielle R., Domann, Frederick E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159831/ https://www.ncbi.nlm.nih.gov/pubmed/25116688 http://dx.doi.org/10.3390/ijms150813916

Ejemplares similares

Cardiovascular Effects of PCB 126 (3,3’,4,4’,5-Pentachlorobiphenyl) in Zebrafish Embryos and Impact of Co-Exposure to Redox Modulating Chemicals
por: Teixidó, Elisabet, et al.
Publicado: (2019)

Dataset of transcriptomic changes that occur in human preadipocytes over a 3-day course of exposure to 3,3′,4,4′,5-Pentachlorobiphenyl (PCB126)
por: Gourronc, Francoise A., et al.
Publicado: (2022)

Updating “Dataset of transcriptomic changes that occur in human preadipocytes over a 3-day course of exposure to 3,3′,4,4′,5-Pentachlorobiphenyl (PCB126)” with additional data on exposure to 2,2′,5,5′-tetrachlorobiphenyl (PCB52) or its 4-hydroxy metabolite (4-OH-PCB52)
por: Gourronc, Francoise A., et al.
Publicado: (2023)

Role of DNA methylation in altered gene expression patterns in adult zebrafish (Danio rerio) exposed to 3, 3’, 4, 4’, 5-pentachlorobiphenyl (PCB 126)
por: Aluru, Neelakanteswar, et al.
Publicado: (2018)

3,3′,4,4′,5-Pentachlorobiphenyl Inhibits Drug Efflux Through P-Glycoprotein in KB-3 Cells Expressing Mutant Human P-Glycoprotein
por: Fujise, Hiroshi, et al.
Publicado: (2004)

Increase in cardiovascular pathology in female sprague-dawley rats following chronic treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3,3′,4,4′,5-pentachlorobiphenyl
por: Jokinen, Micheal P., et al.
Publicado: (2003)

PCB 126 and Other Dioxin-Like PCBs Specifically Suppress Hepatic PEPCK Expression via the Aryl Hydrocarbon Receptor
por: Zhang, Wenshuo, et al.
Publicado: (2012)

Enantiomeric Fractions Reveal Differences in the Atropselective Disposition of 2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) in Wildtype, Cyp2abfgs-Null, and CYP2A6-Humanized Mice
por: Li, Xueshu, et al.
Publicado: (2023)

2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) Is Atropselectively Metabolized to para-Hydroxylated Metabolites by Human Liver Microsomes
por: Uwimana, Eric, et al.
Publicado: (2016)

3,3′-Dinitro-4,4′-bipyridine
por: Wang, Yong, et al.
Publicado: (2011)

CYP1A1, VEGFA and Adipokine Responses of Human Adipocytes Co-exposed to PCB126 and Hypoxia
por: Amine, Zeinab El, et al.
Publicado: (2022)

Examination of the estrogenicity of 2,4,6,2',6'-pentachlorobiphenyl (PCB 104), its hydroxylated metabolite 2,4,6,2',6'-pentachloro-4-biphenylol (HO-PCB 104), and a further chlorinated derivative, 2,4,6,2',4',6'-hexachlorobiphenyl (PCB 155).
por: Fielden, M R, et al.
Publicado: (1997)

Biphenyl-3,3′,4,4′-tetraamine
por: Qian, Hui-Fen, et al.
Publicado: (2010)

3,3′′,4,4′′-Tetramethoxy-1,1′:4′,1′′-terphenyl
por: Kung Pui, Law, et al.
Publicado: (2011)

Molecular Mechanisms of 2, 3′, 4, 4′, 5-Pentachlorobiphenyl-Induced Thyroid Dysfunction in FRTL-5 Cells
por: Yang, Hui, et al.
Publicado: (2015)

3,3′-Dichlorobiphenyl-4,4′-diaminium sulfate
por: Qian, Hui-Fen, et al.
Publicado: (2011)

4,4′-Diiodo-3,3′-dimethoxybiphenyl
por: Ali, Qamar, et al.
Publicado: (2008)

Sustained expression of CYPs and DNA adduct accumulation with continuous exposure to PCB126 and PCB153 through a new delivery method: Polymeric implants
por: Aqil, Farrukh, et al.
Publicado: (2014)

3,3′-[Biphenyl-4,4′-diylbis(oxy)]diphthalic acid
por: Zhao, Ningning, et al.
Publicado: (2011)

Biphenyl-3,3′,4,4′-tetracarboxylic acid dihydrate
por: Li, Fei, et al.
Publicado: (2009)

3,3′-Bis(chloromethyl)-4,4′-diethoxy-1,1′-biphenyl
por: Trad, Hager, et al.
Publicado: (2014)

4,4′-Bipyridine–3,3′-disulfanediylbis(1H-1,2,4-triazole-5-amine) (1/1)
por: Yang, Wei, et al.
Publicado: (2012)

The Relationship between Aryl Hydrocarbon Hydroxylase and Polymorphisms of the CYP1A1 Gene
por: Kiyohara, Chikako, et al.
Publicado: (1996)

Poly[bis(4,4′-bipyridine)(μ(3)-4,4′-dicarboxybiphenyl-3,3′-dicarboxylato)iron(II)]
por: Meng, Qun-Hui, et al.
Publicado: (2009)

Crystal structure of 4,4′-bis(4-bromophenyl)-1,1′,3,3′-tetrathiafulvalene
por: Rigin, Sergei, et al.
Publicado: (2019)

Tris(1,10-phenanthroline)cadmium 3,3′-dicarboxy-4,4′-diazenediyldibenzoate–4,4′-diazenediyldiphthalic acid–methanol (1/0.5/1)
por: Wang, Jun, et al.
Publicado: (2011)

3,3′-Difluoro-4,4′-(p-phenylenedioxy)dibenzonitrile
por: Zhang, Jixu, et al.
Publicado: (2009)

3,3′-Bis(quinolin-8-yl)-1,1′-[4,4′-methylenebis(4,1-phenylene)]diurea
por: Pramanik, Avijit, et al.
Publicado: (2011)

Discovery of Non-Aroclor PCB (3,3′-Dichlorobiphenyl) in Chicago Air
por: Hu, Dingfei, et al.
Publicado: (2008)

1,1′-Bis(4-fluorophenyl)-3,3′-diisobutyl-4,4′-diphenoxy-1H,1′H-4,4′-bipyrazole-5,5′(4H,4′H)-dione
por: Fun, Hoong-Kun, et al.
Publicado: (2011)

Subchronic Exposure to TCDD, PeCDF, PCB126, and PCB153: Effect on Hepatic Gene Expression
por: Vezina, Chad M., et al.
Publicado: (2004)

In Vivo Biotransformation of 3,3′,4,4′-Tetrachlorobiphenyl by Whole Plants−Poplars and Switchgrass
por: Liu, Jiyan, et al.
Publicado: (2009)

Effects of PCB126 on Adipose-to-Muscle Communication in an in Vitro Model
por: Caron, Audrey, et al.
Publicado: (2020)

Effects of Adipocyte Aryl Hydrocarbon Receptor Deficiency on PCB-Induced Disruption of Glucose Homeostasis in Lean and Obese Mice
por: Baker, Nicki A., et al.
Publicado: (2015)

A selective aryl hydrocarbon receptor modulator 3,3'-Diindolylmethane inhibits gastric cancer cell growth
por: Yin, Xiao-Fei, et al.
Publicado: (2012)

3,3′-Dibromo-4,4′-[(1R,2R)-cyclohexane-1,2-diyldiimino]dipent-3-en-2-one
por: Zhang, Yun-Qian, et al.
Publicado: (2008)

The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor
por: Ciolino, H P, et al.
Publicado: (1999)

The aryl hydrocarbon receptor and retinoid receptors cross-talk at the CYP1A1 promoter in vitro
por: Hessel-Pras, Stefanie, et al.
Publicado: (2018)

Skatole (3-Methylindole) Is a Partial Aryl Hydrocarbon Receptor Agonist and Induces CYP1A1/2 and CYP1B1 Expression in Primary Human Hepatocytes
por: Rasmussen, Martin Krøyer, et al.
Publicado: (2016)

3,3′-Dimethyl-4,4′-(hexane-1,6-diyl)bis[1H-1,2,4-triazol-5(4H)-one]
por: Ustabaş, Reşat, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_1fnorru6iecdu08c7g4cdk1fr8