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Localization of MLH3 at the Centrosomes
Mutations in human DNA mismatch repair (MMR) genes are commonly associated with hereditary nonpolyposis colorectal cancer (HNPCC). MLH1 protein heterodimerizes with PMS2, PMS1, and MLH3 to form MutLα, MutLβ, and MutLγ, respectively. We reported recently stable expression of GFP-linked MLH3 in human...
Autores principales: | Roesner, Lennart M., Mielke, Christian, Faehnrich, Silke, Merkhoffer, Yvonne, Dittmar, Kurt E. J., Drexler, Hans G., Dirks, Wilhelm G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159832/ https://www.ncbi.nlm.nih.gov/pubmed/25116689 http://dx.doi.org/10.3390/ijms150813932 |
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