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Melatonin Suppresses Hypoxia-Induced Migration of HUVECs via Inhibition of ERK/Rac1 Activation

Melatonin, a naturally-occurring hormone, possesses antioxidant properties and ameliorates vascular endothelial dysfunction. In this study, we evaluate the impact of melatonin on the migratory capability of human umbilical vein endothelial cells (HUVECs) to hypoxia and further investigate whether ER...

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Detalles Bibliográficos
Autores principales: Yang, Ling, Zheng, Jianchao, Xu, Rui, Zhang, Yujie, Gu, Luo, Dong, Jing, Zhu, Yichao, Zhou, Ruijue, Zheng, Lu, Zhang, Xiaoying, Du, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159841/
https://www.ncbi.nlm.nih.gov/pubmed/25123138
http://dx.doi.org/10.3390/ijms150814102