Functional Cross-Talk between the α(1)- and β(1)-Adrenergic Receptors Modulates the Rapidly Activating Delayed Rectifier Potassium Current in Guinea Pig Ventricular Myocytes

The rapidly activating delayed rectifier potassium current (I(Kr)) plays a critical role in cardiac repolarization. Although I(Kr) is known to be regulated by both α(1)- and β(1)-adrenergic receptors (ARs), the cross-talk and feedback mechanisms that dictate its response to α(1)- and β(1)-AR activat...

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Detalles Bibliográficos
Autores principales: Xu, Di, Wang, Sen, Wu, Ting-Ting, Wang, Xiao-Yan, Qian, Jin, Guo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159847/
https://www.ncbi.nlm.nih.gov/pubmed/25196520
http://dx.doi.org/10.3390/ijms150814220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159847/
https://www.ncbi.nlm.nih.gov/pubmed/25196520
http://dx.doi.org/10.3390/ijms150814220

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