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Functional Cross-Talk between the α(1)- and β(1)-Adrenergic Receptors Modulates the Rapidly Activating Delayed Rectifier Potassium Current in Guinea Pig Ventricular Myocytes
The rapidly activating delayed rectifier potassium current (I(Kr)) plays a critical role in cardiac repolarization. Although I(Kr) is known to be regulated by both α(1)- and β(1)-adrenergic receptors (ARs), the cross-talk and feedback mechanisms that dictate its response to α(1)- and β(1)-AR activat...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159847/ https://www.ncbi.nlm.nih.gov/pubmed/25196520 http://dx.doi.org/10.3390/ijms150814220 |