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Low-Frequency High-Magnitude Mechanical Strain of Articular Chondrocytes Activates p38 MAPK and Induces Phenotypic Changes Associated with Osteoarthritis and Pain

Osteoarthritis (OA) is a debilitating joint disorder resulting from an incompletely understood combination of mechanical, biological, and biochemical processes. OA is often accompanied by inflammation and pain, whereby cytokines associated with chronic OA can up-regulate expression of neurotrophic f...

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Detalles Bibliográficos
Autores principales: Rosenzweig, Derek H., Quinn, Thomas M., Haglund, Lisbet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159860/
https://www.ncbi.nlm.nih.gov/pubmed/25196344
http://dx.doi.org/10.3390/ijms150814427