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Sirt3 Protects Cortical Neurons against Oxidative Stress via Regulating Mitochondrial Ca(2+) and Mitochondrial Biogenesis
Oxidative stress is a well-established event in the pathology of several neurobiological diseases. Sirt3 is a nicotinamide adenine nucleotide (NAD(+))-dependent protein deacetylase that regulates mitochondrial function and metabolism in response to caloric restriction and stress. This study aims to...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159870/ https://www.ncbi.nlm.nih.gov/pubmed/25196599 http://dx.doi.org/10.3390/ijms150814591 |