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Polymorphism of the Flap Endonuclease 1 Gene in Keratoconus and Fuchs Endothelial Corneal Dystrophy

Oxidative stress is implicated in the pathogenesis of many diseases, including serious ocular diseases, keratoconus (KC) and Fuchs endothelial corneal dystrophy (FECD). Flap endonuclease 1 (FEN1) plays an important role in the repair of oxidative DNA damage in the base excision repair pathway. We de...

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Detalles Bibliográficos
Autores principales: Wojcik, Katarzyna A., Synowiec, Ewelina, Polakowski, Piotr, Głowacki, Sylwester, Izdebska, Justyna, Lloyd, Sophie, Galea, Dieter, Blasiak, Janusz, Szaflik, Jerzy, Szaflik, Jacek P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159882/
https://www.ncbi.nlm.nih.gov/pubmed/25153632
http://dx.doi.org/10.3390/ijms150814786