Enhanced dissolution and stability of Tanshinone IIA base by solid dispersion system with nano-hydroxyapatite

BACKGROUND: Tanshinone IIA (TSIIA) exhibits a variety of cardiovascular effects; however, it has low solubility in water. The preparation of poorly soluble drugs for oral delivery is one of the greatest challenges in the field of formulation research. Among the approaches available, solid dispersion...

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Detalles Bibliográficos
Autores principales: Jiang, Yan-rong, Zhang, Zhen-hai, Huang, Sai-yan, Lu, Yan, Ma, Tian-tian, Jia, Xiao-bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159928/
https://www.ncbi.nlm.nih.gov/pubmed/25210322
http://dx.doi.org/10.4103/0973-1296.137375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159928/
https://www.ncbi.nlm.nih.gov/pubmed/25210322
http://dx.doi.org/10.4103/0973-1296.137375

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