Cargando…

Enhanced dissolution and stability of Tanshinone IIA base by solid dispersion system with nano-hydroxyapatite

BACKGROUND: Tanshinone IIA (TSIIA) exhibits a variety of cardiovascular effects; however, it has low solubility in water. The preparation of poorly soluble drugs for oral delivery is one of the greatest challenges in the field of formulation research. Among the approaches available, solid dispersion...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Yan-rong, Zhang, Zhen-hai, Huang, Sai-yan, Lu, Yan, Ma, Tian-tian, Jia, Xiao-bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159928/ https://www.ncbi.nlm.nih.gov/pubmed/25210322 http://dx.doi.org/10.4103/0973-1296.137375

Ejemplares similares

Characterization and Stability of Tanshinone IIA Solid Dispersions with Hydroxyapatite
por: Wang, Xiaopan, et al.
Publicado: (2013)

An attempt to stabilize tanshinone IIA solid dispersion by the use of ternary systems with nano-CaCO(3) and poloxamer 188
por: Yan, Hong-mei, et al.
Publicado: (2014)

Preparation, characterization, and in vivo evaluation of tanshinone IIA solid dispersions with silica nanoparticles
por: Jiang, Yan-rong, et al.
Publicado: (2013)

Preparation and characterisation of solid dispersions of tanshinone IIA, cryptotanshinone and total tanshinones
por: Zhai, Xifeng, et al.
Publicado: (2017)

Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats
por: Yan, Jun, et al.
Publicado: (2016)

Effect of Supplementation of Tanshinone IIA and Sodium Tanshinone IIA Sulfonate on the Anticancer Effect of Epirubicin: An In Vitro Study
por: Chan, Szu-Erh, et al.
Publicado: (2011)

Novel Gliclazide Electrosprayed Nano-Solid Dispersions: Physicochemical Characterization and Dissolution Evaluation
por: Adibkia, Khosro, et al.
Publicado: (2019)

Metabolism of Tanshinone IIA, Cryptotanshinone and Tanshinone I from Radix Salvia Miltiorrhiza in Zebrafish
por: Wei, Yingjie, et al.
Publicado: (2012)

Co-amorphous solid dispersion systems of lacidipine-spironolactone with improved dissolution rate and enhanced physical stability
por: Wang, Zhaomeng, et al.
Publicado: (2019)

Tanshinone IIA: A Review of its Anticancer Effects
por: Fang, Zhong‐ying, et al.
Publicado: (2021)

Enhancement of dissolution of Telmisartan through use of solid dispersion technique - surface solid dispersion
por: Patel, Bhumika, et al.
Publicado: (2012)

Dissolution enhancement of efavirenz by solid dispersion and PEGylation techniques
por: Madhavi, B. Bindu, et al.
Publicado: (2011)

Inhibition of tanshinone IIA on renin activity protected against osteoporosis in diabetic mice
por: Zhang, Jingjing, et al.
Publicado: (2020)

Long-term stability of clopidogrel solid dispersions—Importance of in vitro dissolution test
por: Osmanović Omerdić, Ehlimana, et al.
Publicado: (2022)

Tanshinone IIA: A Promising Natural Cardioprotective Agent
por: Shang, Qinghua, et al.
Publicado: (2012)

Neuron Regeneration and Proliferation Effects of Danshen and Tanshinone IIA
por: Shen, Jui-Lung, et al.
Publicado: (2011)

Anti-Inflammatory and Immunomodulatory Mechanism of Tanshinone IIA for Atherosclerosis
por: Chen, Zhuo, et al.
Publicado: (2014)

Evaluation of Tanshinone IIA Developmental Toxicity in Zebrafish Embryos
por: Wang, Tao, et al.
Publicado: (2017)

Pharmacological Activity and Mechanism of Tanshinone IIA in Related Diseases
por: Guo, Rui, et al.
Publicado: (2020)

Renoprotective Effects of Tanshinone IIA: A Literature Review
por: Chen, Zhengtao, et al.
Publicado: (2023)

Tanshinone IIA reduces secretion of pro-angiogenic factors and inhibits angiogenesis in human colorectal cancer
por: Zhou, Lihong, et al.
Publicado: (2020)

Antifatigue properties of tanshinone IIA in mice subjected to the forced swimming test
por: Lin, Chueh-Yu, et al.
Publicado: (2017)

Transgelin-2 Involves in the Apoptosis of Colorectal Cancer Cells Induced by Tanshinone-IIA
por: Zhang, Yingru, et al.
Publicado: (2022)

Sodium tanshinone IIA sulfonate ameliorates neointima by protecting endothelial progenitor cells in diabetic mice
por: Heng, Yan-Yan, et al.
Publicado: (2023)

Possible mechanisms of treatment for spinal cord injury repair with tanshinone IIA
por: Jia, Zhiwei, et al.
Publicado: (2023)

AMPK activation by Tanshinone IIA protects neuronal cells from oxygen-glucose deprivation
por: Weng, Yingfeng, et al.
Publicado: (2017)

Tanshinone IIA Ameliorates Nonalcoholic Steatohepatitis in Mice by Modulating Neutrophil Extracellular Traps and Hepatocyte Apoptosis
por: Xu, Lianjie, et al.
Publicado: (2022)

Tanshinone IIA Inhibits Osteosarcoma Growth through a Src Kinase-Dependent Mechanism
por: Hu, Chao, et al.
Publicado: (2021)

Sodium tanshinone IIA sulfonate stimulated Cl(−) secretion in mouse trachea
por: Chen, Peng-Xiao, et al.
Publicado: (2017)

The Complex Regulation of Tanshinone IIA in Rats with Hypertension-Induced Left Ventricular Hypertrophy
por: Pang, Hui, et al.
Publicado: (2014)

The Attenuation of Traumatic Brain Injury via Inhibition of Oxidative Stress and Apoptosis by Tanshinone IIA
por: Huang, Yongpan, et al.
Publicado: (2020)

Inhibitory Effect of Tanshinone IIA on Rat Hepatic Stellate Cells
por: Liu, Ya-Wei, et al.
Publicado: (2014)

Tanshinone IIA attenuates bleomycin-induced pulmonary fibrosis in rats
por: HE, HUANYU, et al.
Publicado: (2015)

Tanshinone IIA and hepatocellular carcinoma: A potential therapeutic drug
por: Li, Hu, et al.
Publicado: (2023)

In vitro Dissolution Studies on Solid Dispersions of Mefenamic Acid
por: Rao, K. R. S. Sambasiva, et al.
Publicado: (2011)

In vitro dissolution study of atorvastatin binary solid dispersion
por: Jahan, Rahat, et al.
Publicado: (2013)

Thermodynamics of dissolution and infrared-spectroscopy of solid dispersions of phenacetin
por: Gerasimov, Alexander V., et al.
Publicado: (2016)

Tanshinone IIA alleviates brain damage in a mouse model of neuromyelitis optica spectrum disorder by inducing neutrophil apoptosis
por: Gong, Ye, et al.
Publicado: (2020)

Enhanced production of tanshinone IIA in endophytic fungi Emericella foeniculicola by genome shuffling
por: Zhang, Pengyu, et al.
Publicado: (2018)

Protective effects of tanshinone IIA on endothelial progenitor cells injured by tumor necrosis factor-α
por: WANG, XING-XIANG, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_28sar9vfgo2allapuhfpqt6b24