Neuronal excitation upregulates Tbr1, a high-confidence risk gene of autism, mediating Grin2b expression in the adult brain

The activity-regulated gene expression of transcription factors is required for neural plasticity and function in response to neuronal stimulation. T-brain-1 (TBR1), a critical neuron-specific transcription factor for forebrain development, has been recognized as a high-confidence risk gene for auti...

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Detalles Bibliográficos
Autores principales: Chuang, Hsiu-Chun, Huang, Tzyy-Nan, Hsueh, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159980/
https://www.ncbi.nlm.nih.gov/pubmed/25309323
http://dx.doi.org/10.3389/fncel.2014.00280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159980/
https://www.ncbi.nlm.nih.gov/pubmed/25309323
http://dx.doi.org/10.3389/fncel.2014.00280

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