The emerging role of guanine nucleotide exchange factors in ALS and other neurodegenerative diseases

Small GTPases participate in a broad range of cellular processes such as proliferation, differentiation, and migration. The exchange of GDP for GTP resulting in the activation of these GTPases is catalyzed by a group of enzymes called guanine nucleotide exchange factors (GEFs), of which two classes:...

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Detalles Bibliográficos
Autores principales: Droppelmann, Cristian A., Campos-Melo, Danae, Volkening, Kathryn, Strong, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159981/
https://www.ncbi.nlm.nih.gov/pubmed/25309324
http://dx.doi.org/10.3389/fncel.2014.00282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159981/
https://www.ncbi.nlm.nih.gov/pubmed/25309324
http://dx.doi.org/10.3389/fncel.2014.00282

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