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The emerging role of guanine nucleotide exchange factors in ALS and other neurodegenerative diseases
Small GTPases participate in a broad range of cellular processes such as proliferation, differentiation, and migration. The exchange of GDP for GTP resulting in the activation of these GTPases is catalyzed by a group of enzymes called guanine nucleotide exchange factors (GEFs), of which two classes:...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159981/ https://www.ncbi.nlm.nih.gov/pubmed/25309324 http://dx.doi.org/10.3389/fncel.2014.00282 |