Alpha-synuclein mutations impair axonal regeneration in models of Parkinson's disease

The dopaminergic (DAergic) nigrostriatal tract has an intrinsic regenerative capacity which can be impaired in Parkinson's disease (PD). Alpha-synuclein (aSyn) is a major pathogenic component in PD but its impact on DAergic axonal regeneration is largely unknown. In this study, we expressed pat...

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Detalles Bibliográficos
Autores principales: Tönges, Lars, Szegö, Éva M., Hause, Patrizia, Saal, Kim-Ann, Tatenhorst, Lars, Koch, Jan Christoph, d`Hedouville, Zara, Dambeck, Vivian, Kügler, Sebastian, Dohm, Christoph P., Bähr, Mathias, Lingor, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159996/
https://www.ncbi.nlm.nih.gov/pubmed/25309425
http://dx.doi.org/10.3389/fnagi.2014.00239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159996/
https://www.ncbi.nlm.nih.gov/pubmed/25309425
http://dx.doi.org/10.3389/fnagi.2014.00239

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