Noninvasive in vivo magnetic resonance measures of glutathione synthesis in human and rat liver as an oxidative stress biomarker

Oxidative stress (OS) plays a central role in the progression of liver disease and in damage to liver by toxic xenobiotics. We have developed methods for noninvasive assessment of hepatic OS defenses by measuring flux through the glutathione (GSH) synthesis pathway. (13)C-labeled GSH is endogenously...

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Detalles Bibliográficos
Autores principales: Skamarauskas, John T, Oakley, Fiona, Smith, Fiona E, Bawn, Carlo, Dunn, Michael, Vidler, Daniel S, Clemence, Matthew, Blain, Peter G, Taylor, Roy, Gamcsik, Michael P, Thelwall, Peter E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Liver Injury/Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160151/
https://www.ncbi.nlm.nih.gov/pubmed/24242936
http://dx.doi.org/10.1002/hep.26925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160151/
https://www.ncbi.nlm.nih.gov/pubmed/24242936
http://dx.doi.org/10.1002/hep.26925

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