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Engineering Amyloid-Like Assemblies from Unstructured Peptides via Site-Specific Lipid Conjugation
Aggregation of amyloid beta (Aβ) into oligomers and fibrils is believed to play an important role in the development of Alzheimer’s disease (AD). To gain further insight into the principles of aggregation, we have investigated the induction of β-sheet secondary conformation from disordered native pe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160191/ https://www.ncbi.nlm.nih.gov/pubmed/25207975 http://dx.doi.org/10.1371/journal.pone.0105641 |