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Nanoparticle-Assisted Targeted Delivery of Eye-Specific Genes to Eyes Significantly Improves the Vision of Blind Mice In Vivo

[Image: see text] Application of viruses as a carrier, though not safe, to deliver genes to eye tissue was successful. However, a safer, nonviral, biocompatible lipid-based nanoparticle has never been tested to treat blinding eye diseases. We created an artificial virus using a nanoparticle, liposom...

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Detalles Bibliográficos
Autores principales: Rajala, Ammaji, Wang, Yuhong, Zhu, Ye, Ranjo-Bishop, Michelle, Ma, Jian-Xing, Mao, Chuanbin, Rajala, Raju V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160266/
https://www.ncbi.nlm.nih.gov/pubmed/25115433
http://dx.doi.org/10.1021/nl502275s