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Nanoparticle-Assisted Targeted Delivery of Eye-Specific Genes to Eyes Significantly Improves the Vision of Blind Mice In Vivo
[Image: see text] Application of viruses as a carrier, though not safe, to deliver genes to eye tissue was successful. However, a safer, nonviral, biocompatible lipid-based nanoparticle has never been tested to treat blinding eye diseases. We created an artificial virus using a nanoparticle, liposom...
Autores principales: | Rajala, Ammaji, Wang, Yuhong, Zhu, Ye, Ranjo-Bishop, Michelle, Ma, Jian-Xing, Mao, Chuanbin, Rajala, Raju V. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160266/ https://www.ncbi.nlm.nih.gov/pubmed/25115433 http://dx.doi.org/10.1021/nl502275s |
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