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Genome-wide screening identifies new genes required for stress-induced phase 2 detoxification gene expression in animals

BACKGROUND: Phase 2 detoxification enzymes provide a vital defence against reactive oxygen species, including xenobiotic metabolites, which cause the oxidative damage involved in drug toxicity and many diseases. Hence, there is great interest in understanding how levels of these enzymes are regulate...

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Detalles Bibliográficos
Autores principales: Crook-McMahon, Helen M, Oláhová, Monika, Button, Emma L, Winter, Johnathan J, Veal, Elizabeth A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160539/
https://www.ncbi.nlm.nih.gov/pubmed/25204677
http://dx.doi.org/10.1186/s12915-014-0064-6