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Genome-wide screening identifies new genes required for stress-induced phase 2 detoxification gene expression in animals
BACKGROUND: Phase 2 detoxification enzymes provide a vital defence against reactive oxygen species, including xenobiotic metabolites, which cause the oxidative damage involved in drug toxicity and many diseases. Hence, there is great interest in understanding how levels of these enzymes are regulate...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160539/ https://www.ncbi.nlm.nih.gov/pubmed/25204677 http://dx.doi.org/10.1186/s12915-014-0064-6 |