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Evaluation of the antitumor effects of c-Myc-Max heterodimerization inhibitor 100258-F4 in ovarian cancer cells

Epithelial ovarian carcinoma is the most lethal gynecological cancer due to its silent onset and recurrence with resistance to chemotherapy. Overexpression of oncogene c-Myc is one of the most frequently encountered events present in ovarian carcinoma. Disrupting the function of c-Myc and its downst...

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Detalles Bibliográficos
Autores principales: Wang, Jiandong, Ma, Xiaoli, Jones, Hannah M, Chan, Leo Li-Ying, Song, Fang, Zhang, Weiyuan, Bae-Jump, Victoria L, Zhou, Chunxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160551/
https://www.ncbi.nlm.nih.gov/pubmed/25143136
http://dx.doi.org/10.1186/s12967-014-0226-x