Cargando…
Evaluation of the antitumor effects of c-Myc-Max heterodimerization inhibitor 100258-F4 in ovarian cancer cells
Epithelial ovarian carcinoma is the most lethal gynecological cancer due to its silent onset and recurrence with resistance to chemotherapy. Overexpression of oncogene c-Myc is one of the most frequently encountered events present in ovarian carcinoma. Disrupting the function of c-Myc and its downst...
Autores principales: | Wang, Jiandong, Ma, Xiaoli, Jones, Hannah M, Chan, Leo Li-Ying, Song, Fang, Zhang, Weiyuan, Bae-Jump, Victoria L, Zhou, Chunxiao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160551/ https://www.ncbi.nlm.nih.gov/pubmed/25143136 http://dx.doi.org/10.1186/s12967-014-0226-x |
Ejemplares similares
-
Disruption of Myc-Max Heterodimerization with Improved Cell-Penetrating Analogs of the Small Molecule 10074-G5
por: Wang, Huabo, et al.
Publicado: (2013) -
MYC–MAX heterodimerization is essential for the induction of major zygotic genome activation and subsequent preimplantation development
por: Yamamoto, Takuto, et al.
Publicado: (2023) -
Erratum: Disruption of Myc-Max Heterodimerization with Improved Cell-Penetrating Analogs of the Small Molecule 10074-G5
por: Wang, Huabo, et al.
Publicado: (2018) -
A novel inhibitor L755507 efficiently blocks c-Myc–MAX heterodimerization and induces apoptosis in cancer cells
por: Singh, Ashutosh, et al.
Publicado: (2021) -
Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability
por: Yao, Ruosi, et al.
Publicado: (2022)